NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By


 
Result: 1 - 6 of 6 rows are displayed

Molecule List for pathway AC (Pathway Number 197) in Accession PKA_2003 (Accession Number 47)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 ATPNetwork50000Yes
    ATP is present in all cells between 2 and 10 mM. See Lehninger. It is assumed buffered since the metabolic activity will take care of its levels.
2 AMPNetwork10000Yes
    Assumed buffered to 1 mM. Value is irrelevant to simulation.
3 cAMP-PDENetwork0.50No
    The levels of the PDE are not known at this time. However, enough kinetic info and info about steady-state levels of cAMP etc are around to make it possible to estimate this at about 0.5 uM.
4 ACNetwork0.0150No
    AC is present at rather low levels. Here we use 0.015 uM which is meant to lump various isoforms. None of the isoforms nor the other specific regulators are included here. Jacobowitz, PhD thesis.
5 cAMP-PDE*Network00No
    This form has about 2X activity as plain PDE. See Sette et al (1994 Jul 15) J Biol Chem. 269(28):18271-4
6 Gs.ACNetwork00No
    This is the active form of the cyclase.

 
Result: 1 - 6 of 6 rows are displayed



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.